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Spiliotis et al. (2005) found that septins localized to the metaphase plate during mitosis. Septin depletion resulted in chromosome loss from the metaphase plate, lack of chromosome segregation and spindle elongation, and incomplete cytokinesis upon delayed mitotic exit.
STIM1 is a calcium sensor that conveys the calcium load of the endoplasmic reticulum (ER) to store-operated channels (SOCs) at the plasma membrane (Yuan et al., 2007). Using sequences identified by database searching with a transcript from human chromosome 11p15.5, Parker et al. (1996) screened ...
Spinning disk confocal laser microscopy (SDCLM) overcomes this problem by exploiting the multiplex principle. Figure 1c illustrates how the sample is illuminated, and so light detected, at multiple points simultaneously.
Cell - Regulation of RNA after synthesis: After synthesis, RNA molecules undergo selective processing, which results in the export of only a subpopulation of RNA molecules to the cytoplasm.
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Running Times - January/February 2013