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Septins are enriched in the mid-cell zone and at the cell cortex and expand also into the uropod. The role of septins in T-cell morphology and migration has been studied by shRNA-mediated downregulation of septin 7, which also suppresses expression of the other isoforms.
septins led to loss of the neck filaments 6 in addition to loss of the other septins from the bud neck as judged by immunofluorescence4,5. Taken together, these studies suggested that the septins are struc-tural components of the bud neck filaments. The neck filaments were considered a peculiarity
The SEPT9 gene provides instructions for making a protein called septin-9, which is part of a group of proteins called septins. Septins are involved in a process called cytokinesis, which is the step in cell division when the fluid inside the cell (cytoplasm) divides to form two separate cells.
The SEPT9 gene provides instructions for making a protein called septin-9, which is part of a group of proteins called septins. Septins are involved in a process called cytokinesis, which is the step in cell division when the fluid inside the cell (cytoplasm) divides to form two separate cells.
















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| | | | | | Running Times - January/February 2013