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Septins have been found in diverse eukaryotes, including animals and fungi but not protozoa and plants. Most septin genes generate one or more polypeptides by alternative splicing and/or multiple translation start sites; the number of variants is not yet established for many of the genes.
Septins are a family of proteins highly conserved in eukaryotes that have been under intense scrutiny lately because they appear to comprise a novel component of the cytoskeleton.

septins led to loss of the neck filaments 6 in addition to loss of the other septins from the bud neck as judged by immunofluorescence4,5. Taken together, these studies suggested that the septins are struc-tural components of the bud neck filaments. The neck filaments were considered a peculiarity

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| | | | | | Running Times - January/February 2013